Abstract
In a double-blind, placebo-controlled trial comparing alprazolam and imipramine for panic disorder, serum analysis revealed that a substantial proportion of the patients took explicitly prohibited anxiolytic medication. Excluding these patients changed the results.
Publication types
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Clinical Trial
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Controlled Clinical Trial
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Alprazolam / therapeutic use
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Anti-Anxiety Agents / administration & dosage*
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Anxiety Disorders / drug therapy*
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Clinical Trials as Topic / standards
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Double-Blind Method
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Fear*
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Female
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Humans
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Imipramine / therapeutic use
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Male
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Outcome and Process Assessment, Health Care
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Panic*
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Patient Compliance
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Placebos
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Self Medication*
Substances
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Anti-Anxiety Agents
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Placebos
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Imipramine
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Alprazolam