Palladium-catalyzed dehydrogenative coupling of furans with styrenes

Org Lett. 2009 Sep 17;11(18):4096-9. doi: 10.1021/ol901570p.

Abstract

Under palladium(II)-catalyzed and oxidative conditions, the coupling of furans with styrenes leads to the formation of Heck-type products in medium to good yields. The reaction is highly regio- and stereoselective, giving trans-olefins predominantly.

MeSH terms

  • Alkenes / chemical synthesis*
  • Catalysis
  • Furans / chemistry*
  • Oxidation-Reduction
  • Oxygen / chemistry
  • Palladium / chemistry*
  • Stereoisomerism
  • Styrenes / chemistry*

Substances

  • Alkenes
  • Furans
  • Styrenes
  • Palladium
  • Oxygen