A cohort study of the risk of cancer associated with type 2 diabetes

Br J Cancer. 2009 Oct 6;101(7):1199-201. doi: 10.1038/sj.bjc.6605240. Epub 2009 Aug 18.

Abstract

Background: There is evidence to suggest that diabetes may increase the risk of incidence and mortality from cancer.

Methods: In a cohort study using record-linkage health-care datasets for Tayside, Scotland in 1993-2004, we followed up 9577 newly diagnosed patients with type 2 diabetes, and two matched non-diabetic comparators, in the national cancer register.

Results and conclusions: The risk ratio for any cancer, adjusted for deprivation, was 0.99 (95%CI 0.90-1.09). Significantly increased risks were observed for pancreatic, liver and colon cancer.

MeSH terms

  • Cohort Studies
  • Colonic Neoplasms / etiology
  • Diabetes Mellitus, Type 2 / complications*
  • Female
  • Humans
  • Liver Neoplasms / etiology
  • Male
  • Middle Aged
  • Neoplasms / epidemiology
  • Neoplasms / etiology*
  • Pancreatic Neoplasms / etiology
  • Risk
  • Scotland / epidemiology
  • Time Factors