Neurosurgery for obsessive-compulsive disorder: contemporary approaches

J Clin Neurosci. 2010 Jan;17(1):1-5. doi: 10.1016/j.jocn.2009.02.043. Epub 2009 Aug 14.

Abstract

Surgery for psychiatric disorders has a controversial history. Traditionally, procedures were undertaken to physically disconnect or destroy certain areas of the brain thought to constitute critical components of the limbic pathways. The relatively recent advent of the much safer and non-destructive technique known as deep brain stimulation has coincided with a resurgence in interest in psychosurgery. Contemporary approaches to the surgical management of obsessive-compulsive disorder are discussed, together with our current understanding of its pathophysiology.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Brain / metabolism
  • Brain / physiopathology*
  • Brain / surgery*
  • Deep Brain Stimulation / methods
  • Deep Brain Stimulation / trends*
  • History, 20th Century
  • Humans
  • Neural Pathways / metabolism
  • Neural Pathways / physiopathology
  • Neural Pathways / surgery
  • Neuropharmacology / history
  • Neuropharmacology / methods
  • Neuropharmacology / trends
  • Obsessive-Compulsive Disorder / drug therapy
  • Obsessive-Compulsive Disorder / physiopathology*
  • Obsessive-Compulsive Disorder / surgery*
  • Postoperative Complications / prevention & control
  • Psychosurgery / adverse effects
  • Psychosurgery / history*
  • Psychosurgery / methods
  • Psychotherapy / history
  • Psychotherapy / methods
  • Psychotherapy / trends
  • Risk Assessment