Association of the bla(CMY-10) gene with a novel complex class 1 integron carrying an ISCR1 element in clinical isolates from Korea

J S Song; S J Jang; J J Lee; J H Lee; I K Bae; B C Jeong; S-S Cha; J-H Lee; S-K Hong; S H Lee

doi:10.1111/j.1469-0691.2009.03002.x

Association of the bla(CMY-10) gene with a novel complex class 1 integron carrying an ISCR1 element in clinical isolates from Korea

Clin Microbiol Infect. 2010 Jul;16(7):1013-7. doi: 10.1111/j.1469-0691.2009.03002.x. Epub 2009 Jul 21.

Authors

J S Song¹, S J Jang, J J Lee, J H Lee, I K Bae, B C Jeong, S-S Cha, J-H Lee, S-K Hong, S H Lee

Affiliation

¹ Department of Biological Sciences, Drug Resistance Proteomics Laboratory, Myongji University, Yongin, Gyeonggido, Korea.

PMID: 19681956
DOI: 10.1111/j.1469-0691.2009.03002.x

Abstract

The bla(CMY-10) gene responsible for β-lactam resistance was located on a new complex class 1 integron within a conjugative plasmid. The sul1-type class 1 integron, containing an aadA2a gene cassette, was identified upstream of bla(CMY-10). A unique gene array (yqgF-yqgE-gshB-orf97--orf105) was identified downstream of bla(CMY-10.).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
DNA, Bacterial / genetics
Enterobacter aerogenes / drug effects
Enterobacter aerogenes / genetics*
Enterobacter aerogenes / isolation & purification
Enterobacteriaceae Infections / microbiology
Escherichia coli / genetics
Genes, Bacterial
Humans
Integrons / genetics*
Microbial Sensitivity Tests
Molecular Sequence Data
Polymerase Chain Reaction
Republic of Korea
Sequence Analysis, DNA
beta-Lactam Resistance / genetics*
beta-Lactamases / genetics*

Substances

DNA, Bacterial
CMY-10 beta-lactamase
beta-Lactamases

Associated data

GENBANK/FJ004895