Treatment of functional menorrhagia by radiofrequency-induced thermal endometrial ablation

Lancet. 1990 Feb 17;335(8686):374-6. doi: 10.1016/0140-6736(90)90207-l.

Abstract

42 patients were enrolled in a trial of radiofrequency-induced thermal endometrial ablation for the treatment of functional menorrhagia. The radiofrequency electromagnetic energy was delivered via a probe placed within the endometrial cavity. 10 patients received 330 kJ of energy, 10 received 445 kJ, and the other 22 received 660 kJ. 19 (87%) of those receiving the highest dose became amenorrheic or had a considerable reduction in menstrual flow. The procedure is simple and the heat induced in the endometrium does not penetrate much beyond the inner layers of the myometrium. There is no need for distension of the uterine cavity with flushing media.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Dose-Response Relationship, Radiation
  • Endometrium / radiation effects*
  • Evaluation Studies as Topic
  • Female
  • Follow-Up Studies
  • Humans
  • Hyperthermia, Induced / methods*
  • Menorrhagia / physiopathology
  • Menorrhagia / radiotherapy*
  • Middle Aged