Unexpected synthesis of N-methylbenzo[d]isoxazolium hydroxides under microwave irradiation conditions

Mol Divers. 2010 Aug;14(3):575-9. doi: 10.1007/s11030-009-9189-x. Epub 2009 Aug 14.

Abstract

Microwave-assisted condensation of salicylaldehydes and N-methyl hydroxylammonium hydrochloride in the presence of K(2)CO(3) under solvent-free conditions afforded, unexpected N-methylbenzo[d]isoxazolium hydroxides (2a-d).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Amines / chemistry
  • Chemistry, Organic / methods*
  • Hydroxides / chemical synthesis*
  • Hydroxides / chemistry
  • Hydroxylamine / chemistry
  • Microwaves*
  • Nitrogen Oxides / chemical synthesis
  • Nitrogen Oxides / chemistry
  • Solvents / chemistry

Substances

  • Aldehydes
  • Amines
  • Hydroxides
  • Nitrogen Oxides
  • Solvents
  • nitrones
  • salicylaldehyde
  • Hydroxylamine