Abstract
Some fused heterocyclic pyrimidines have been synthesized in high yields using ultrasound irradiation in a one-pot, three-component and efficient process by condensation reaction of barbituric acids, aldehydes and a series of enamines in water. Prominent among the advantages of this new method are operational simplicity, good yields in short reaction times and easy work-up procedures employed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehydes / chemistry
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Aldehydes / radiation effects
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Amines / chemistry
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Amines / radiation effects
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Barbiturates / chemistry
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Barbiturates / radiation effects
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Heterocyclic Compounds / chemistry*
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Heterocyclic Compounds / radiation effects*
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Pyrimidines / chemical synthesis*
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Pyrimidines / radiation effects*
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Radiation Dosage
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Sonication / methods*
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Water / chemistry
Substances
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Aldehydes
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Amines
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Barbiturates
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Heterocyclic Compounds
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Pyrimidines
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Water
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barbituric acid