[Vitamin D deficiency]

Ugeskr Laeger. 2009 Jun 22;171(26):2179-84.
[Article in Danish]

Abstract

The importance of vitamin D for osteoporosis and fractures has been known for more than 40 years. Vitamin D deficiency is diagnosed by measuring 25-hydroxyvitamin D (25-OHD), which should be > 50 nmol/l year round. Recent research suggests that a number of severe diseases could be prevented by increasing 25-OHD to 80 nmol/l. Despite a strong focus on such increase, recommendations for intake of Vitamin D have not been changed and the present recommendations are too low even to ensure > 50 nmol/l. To achieve optimal concentrations > 80 nmol/l, we estimate that 50-70 microgram of vitamin D per day for everyone from the age of 10 years is necessary. Until the safety of this dose has been further documented, we recommend 35-38 micrograms/day.

Publication types

  • Review

MeSH terms

  • Adult
  • Child
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Male
  • Nutritional Requirements
  • Osteoporosis / prevention & control
  • Reference Values
  • Ultraviolet Rays
  • Vitamin D / administration & dosage
  • Vitamin D / analogs & derivatives
  • Vitamin D / blood
  • Vitamin D Deficiency* / complications
  • Vitamin D Deficiency* / drug therapy
  • Vitamin D Deficiency* / prevention & control

Substances

  • Vitamin D
  • 25-hydroxyvitamin D