A major question in today's neuroscience is how the brain's complex operations and organization emerge from individual components. The robustness of neuronal properties with flexible linkages between regulatory processes conceivably accounts for the adaptive, tunable, multistable dynamics; the coding schemes; and the complexity of neuronal functional (sub)systems. Interneurons and neurotransmitter diversity, resonance phenomena due to properties of the cell, time/frequency-dependent activation of dedicated neuronal assemblies, and code- and frequency-specific oscillations interact in determining the brain functional setup and operations. Such an arrangement would also provide the functional requirements for access to neural mechanisms, dedicated neuronal circuitry and the proper timing allowing for the selective differentiation among cortical neurons due to performing in different tasks. No comprehensive theory or systematic methodological approach appears yet conceivable. The scenario, however incomplete and incompletely characterized, is nevertheless promising and warrants further investigation.