Abstract
The organic Lewis base-catalysed asymmetric allylic alkylation of 3-substituted oxindoles with Morita-Baylis-Hillman carbonates is reported, affording multifunctional oxindoles with adjacent quaternary and tertiary chiral centres (dr up to 92 : 8, 86-97% ee).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkylation
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Allyl Compounds / chemistry*
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Carbonates / chemistry*
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Catalysis
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Cinchona Alkaloids / chemistry*
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Indoles / chemistry*
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Molecular Structure
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Oxindoles
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Stereoisomerism
Substances
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Allyl Compounds
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Carbonates
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Cinchona Alkaloids
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Indoles
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Oxindoles
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2-oxindole