Rapid detection of vaginal Candida species by newly developed immunochromatography

Hidehito Matsui; Hideaki Hanaki; Kengo Takahashi; Akihiko Yokoyama; Taiji Nakae; Keisuke Sunakawa; Satoshi Omura

doi:10.1128/CVI.00204-09

Rapid detection of vaginal Candida species by newly developed immunochromatography

Clin Vaccine Immunol. 2009 Sep;16(9):1366-8. doi: 10.1128/CVI.00204-09. Epub 2009 Aug 5.

Authors

Hidehito Matsui¹, Hideaki Hanaki, Kengo Takahashi, Akihiko Yokoyama, Taiji Nakae, Keisuke Sunakawa, Satoshi Omura

Affiliation

¹ Laboratory for Antimicrobial Agents, Kitasato University, 5-9-1 Shirokane, Minato-Ku, Tokyo 108-8641, Japan.

Abstract

For the diagnosis of vulvovaginal candidiasis, we developed a simple immunochromatographic method that enables the detection of vaginal Candida spp. within about 30 min. Overall, the sensitivity, specificity, positive predictive value, and negative predictive value of this method appeared to be 80.3, 99.3, 98.0, and 92.0%, respectively.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Antigens, Fungal / isolation & purification*
Candida / chemistry*
Candidiasis, Vulvovaginal / diagnosis*
Clinical Laboratory Techniques / methods*
Female
Humans
Immunoassay / methods*
Sensitivity and Specificity
Time Factors

Substances

Antigens, Fungal