Naseseazines A and B: a new dimeric diketopiperazine framework from a marine-derived actinomycete, Streptomyces sp

Ritesh Raju; Andrew M Piggott; Melissa Conte; William G L Aalbersberg; Klaus Feussner; Robert J Capon

doi:10.1021/ol901466r

Naseseazines A and B: a new dimeric diketopiperazine framework from a marine-derived actinomycete, Streptomyces sp

Org Lett. 2009 Sep 3;11(17):3862-5. doi: 10.1021/ol901466r.

Authors

Ritesh Raju¹, Andrew M Piggott, Melissa Conte, William G L Aalbersberg, Klaus Feussner, Robert J Capon

Affiliation

¹ Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.

PMID: 19655766
DOI: 10.1021/ol901466r

Abstract

Chemical analysis of a Streptomyces sp. (CMB-MQ030) isolated from a Fijian marine sediment yielded two new diketopiperazines, naseseazines A and B (1, 2), featuring a new dimeric framework. Structures were determined by detailed spectroscopic analysis and C(3) Marfey's analysis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Actinobacteria / chemistry
Diketopiperazines / chemistry
Diketopiperazines / isolation & purification*
Fiji
Marine Biology
Molecular Structure
Streptomyces / chemistry*

Substances

Diketopiperazines
naseseazine A
naseseazine B