Cobalt(II)-responsive DNA binding of a GCN4-bZIP protein containing cysteine residues functionalized with iminodiacetic acid

Angew Chem Int Ed Engl. 2009;48(37):6853-6. doi: 10.1002/anie.200902888.

Authors

Yusuke Azuma¹, Miki Imanishi, Tomoyuki Yoshimura, Takeo Kawabata, Shiroh Futaki

Affiliation

¹ Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan.

PMID: 19655361
DOI: 10.1002/anie.200902888

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Basic-Leucine Zipper Transcription Factors / chemistry*
Basic-Leucine Zipper Transcription Factors / genetics
Basic-Leucine Zipper Transcription Factors / metabolism
Cobalt / chemistry*
Cysteine / chemistry*
DNA / chemistry
DNA-Binding Proteins / chemistry*
Imino Acids / chemistry*
Leucine Zippers
Molecular Sequence Data
Mutation
Protein Binding
Protein Engineering / methods*
Protein Structure, Tertiary
Saccharomyces cerevisiae Proteins / chemistry*
Saccharomyces cerevisiae Proteins / genetics
Saccharomyces cerevisiae Proteins / metabolism

Substances

Basic-Leucine Zipper Transcription Factors
DNA-Binding Proteins
GCN4 protein, S cerevisiae
Imino Acids
Saccharomyces cerevisiae Proteins
Cobalt
DNA
Cysteine
iminodiacetic acid