Diagnosis and management of hereditary colorectal cancer syndromes: Lynch syndrome as a model

CMAJ. 2009 Sep 1;181(5):273-80. doi: 10.1503/cmaj.071574. Epub 2009 Aug 4.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adaptor Proteins, Signal Transducing / genetics
  • Colorectal Neoplasms, Hereditary Nonpolyposis / diagnosis*
  • Colorectal Neoplasms, Hereditary Nonpolyposis / genetics
  • Colorectal Neoplasms, Hereditary Nonpolyposis / therapy*
  • DNA Glycosylases / genetics
  • Disease Management*
  • Genetic Predisposition to Disease
  • Genetic Testing*
  • Germ-Line Mutation
  • Humans
  • MutL Protein Homolog 1
  • MutL Proteins
  • Neoplasm Proteins / genetics
  • Nuclear Proteins / genetics
  • Pedigree
  • Practice Guidelines as Topic
  • Referral and Consultation

Substances

  • Adaptor Proteins, Signal Transducing
  • MLH1 protein, human
  • Neoplasm Proteins
  • Nuclear Proteins
  • PMS1 protein, human
  • DNA Glycosylases
  • mutY adenine glycosylase
  • MutL Protein Homolog 1
  • MutL Proteins