First expeditious synthesis of 6,11-diamino-[6]carbohelicenes

Chem Commun (Camb). 2009 Aug 28:(32):4827-8. doi: 10.1039/b905670j. Epub 2009 Jul 14.

Abstract

The first synthesis of 6,11-diamino-[6]carbohelicenes is described: the short 5 step sequence involves Suzuki-Miyaura coupling, functional group transformations and electrophilic aromatic cyclisation; the original strategy allows the preparation of di- and tetra-substituted helicenes in comfortable yields.