Evaluation of population variation at 17 autosomal STR and 16 Y-STR haplotype loci in Croatians

Naim Haliti; Mirela Carapina; Marijana Masić; Davor Strinović; Irena Martinović Klarić; Milovan Kubat

doi:10.1016/j.fsigen.2008.11.004

Evaluation of population variation at 17 autosomal STR and 16 Y-STR haplotype loci in Croatians

Forensic Sci Int Genet. 2009 Sep;3(4):e137-8. doi: 10.1016/j.fsigen.2008.11.004. Epub 2008 Dec 27.

Authors

Naim Haliti¹, Mirela Carapina, Marijana Masić, Davor Strinović, Irena Martinović Klarić, Milovan Kubat

Affiliation

¹ Department for Legal Medicine and Missing Persons, Faculty of Medicine, University of Pristhina, Mother Teresa Sq., 38000 Pristhina, Kosovo.

PMID: 19647700
DOI: 10.1016/j.fsigen.2008.11.004

Abstract

Seventeen autosomal STR loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, VWA, TPOX, D18S51, D5S818, FGA, Penta E and Penta D) and 16 Y-STR haplotype loci (DYS19, DYS385, DYS389I, DYS398II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635 and GATA H4.1) were analyzed in the sample of 200 unrelated Croatians. The agreement with HWE was confirmed for all autosomal STR loci. The combined power of discrimination (PD) and the combined power of exclusion (PE) for the 17 autosomal STR loci were 0.999999999999999999682299331476 and 0.99999995, respectively. Penta E proved to be the most informative autosomal STR locus. Among 200 Croatian males, 197 Y-STR haplotypes were identified and haplotype diversity was estimated at 0.9998+/-0.0005.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Chromosomes, Human, Y*
Croatia
DNA / blood
DNA / genetics
DNA / isolation & purification
Forensic Medicine / methods
Gene Frequency
Genetics, Population*
Haplotypes*
Humans
Male
Microsatellite Repeats / genetics*
Nucleic Acid Amplification Techniques
Paternity
Polymerase Chain Reaction
Quality Control
Reference Standards

Substances

DNA