A concise total synthesis of (+/-)-acutifolone A

Org Biomol Chem. 2009 Aug 21;7(16):3285-90. doi: 10.1039/b905910e. Epub 2009 Jun 19.

Abstract

Starting from 4-methylcyclohexanone (7), a concise total synthesis of the pinguisane-type sesquiterpenoid acutifolone A, in racemic form, has been accomplished in 14 steps with an overall yield of 14.5%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclization
  • Cyclohexanes / chemistry*
  • Diazonium Compounds / chemistry*
  • Molecular Structure
  • Oxygen / chemistry*
  • Stereoisomerism

Substances

  • Cyclohexanes
  • Diazonium Compounds
  • Cyclohexane
  • Oxygen