Abstract
PTPN7 is a protein tyrosine phosphatase responsible for inactivation of MAPK in leukocytes. Here we report the backbone resonance assignments of the 34 kDa phosphatase domain of human PTPN7, which is amplified in myeloid malignancies and deleted in lymphoproliferative disorders.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Carbon Isotopes / chemistry
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Catalysis
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Magnetic Resonance Spectroscopy / methods*
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Molecular Sequence Data
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Molecular Weight
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Nitrogen Isotopes / chemistry
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Protein Structure, Tertiary
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Protein Tyrosine Phosphatases, Non-Receptor / chemistry*
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Protons
Substances
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Carbon Isotopes
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Nitrogen Isotopes
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Protons
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PTPN7 protein, human
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Protein Tyrosine Phosphatases, Non-Receptor