Abstract
The carboxy-terminal pleckstrin homology (PH) domain recruits GRP1 to the plasma membrane through the specific binding to phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P(3)]. Here, we describe backbone and side chain assignments of the GRP1 PH domain determined by triple resonance experiments.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Amino Acid Sequence
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Carbon Isotopes / chemistry
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Magnetic Resonance Spectroscopy / methods*
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Molecular Sequence Data
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Nitrogen Isotopes / chemistry
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Protein Structure, Tertiary
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Protons
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Receptors, Cytoplasmic and Nuclear / chemistry*
Substances
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Carbon Isotopes
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Nitrogen Isotopes
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Protons
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Receptors, Cytoplasmic and Nuclear
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phosphatidylinositol receptors