Sequence-specific 1H, 13C, and 15N resonance assignments of GRP1 PH domain

Biomol NMR Assign. 2008 Dec;2(2):97-9. doi: 10.1007/s12104-008-9094-8. Epub 2008 May 21.

Abstract

The carboxy-terminal pleckstrin homology (PH) domain recruits GRP1 to the plasma membrane through the specific binding to phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P(3)]. Here, we describe backbone and side chain assignments of the GRP1 PH domain determined by triple resonance experiments.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Amino Acid Sequence
  • Carbon Isotopes / chemistry
  • Magnetic Resonance Spectroscopy / methods*
  • Molecular Sequence Data
  • Nitrogen Isotopes / chemistry
  • Protein Structure, Tertiary
  • Protons
  • Receptors, Cytoplasmic and Nuclear / chemistry*

Substances

  • Carbon Isotopes
  • Nitrogen Isotopes
  • Protons
  • Receptors, Cytoplasmic and Nuclear
  • phosphatidylinositol receptors