Herpes zoster causing skin eruptions and neuropathic pain is routinely seen in the clinical setting. We present an interesting case of weakness involving more than one nerve root level secondary to shingles. The differential diagnosis of lower extremity weakness is long. While a polyradiculopathy secondary to herpes zoster infection is rare, it must be considered in a patient with dermatomal involvement. A thorough history and physical examination with appropriate diagnostic testing is essential to establish the correct diagnosis and thus the appropriate treatment. We present a retrospective review of a case of polyradiculopathy secondary to herpes zoster infection.