Abstract
ACTH dependent Cushing syndrome accounts for approximately 80% of all Cushing syndrome. Distinguishing the pituitary origin from ectopic one is still a diagnosis problem in some cases, especially in bronchial carcinoids, because approximately 50% show cortisol suppresion after dexametasone and may be small and, therefore, difficult to detect in chest radiography. We present a case of a patient with ACTH dependent Cushing syndrome of difficult localization with usual diagnosis tests.
MeSH terms
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ACTH Syndrome, Ectopic / blood
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ACTH Syndrome, Ectopic / complications
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ACTH Syndrome, Ectopic / diagnosis*
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Adrenocorticotropic Hormone / analysis
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Adult
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Biomarkers, Tumor / analysis
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Bronchial Neoplasms / chemistry
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Bronchial Neoplasms / diagnosis
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Bronchial Neoplasms / diagnostic imaging
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Bronchial Neoplasms / metabolism*
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Bronchial Neoplasms / surgery
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Bronchoscopy
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Carcinoid Tumor / chemistry
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Carcinoid Tumor / diagnosis
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Carcinoid Tumor / diagnostic imaging
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Carcinoid Tumor / metabolism*
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Carcinoid Tumor / surgery
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Cushing Syndrome / etiology*
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Diagnostic Errors*
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False Negative Reactions
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Female
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Humans
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Hypophysectomy
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Pituitary ACTH Hypersecretion / diagnosis*
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Pneumonectomy
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Radiography
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Unnecessary Procedures
Substances
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Biomarkers, Tumor
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Adrenocorticotropic Hormone