[Lipid control in diabetic patients in Extremadura (Spain)]

Endocrinol Nutr. 2009 Mar;56(3):112-7. doi: 10.1016/S1575-0922(09)70840-X. Epub 2009 May 18.
[Article in Spanish]

Abstract

Objective: Our study aimed to assess the prevalence and degree of control of dyslipemia, using the 2004 National Cholesterol Education Program criteria, as well as the use of cholesterol lowering drugs in a sample of diabetic patients followed up in primary care settings in Extremadura.

Patients and methods: In this crosssectional, multicenter study the prevalence and control of cardiovascular risk factors was assessed in a sample of 1022 patients having at least one cardiovascular risk factors who were recruited by general practitioners. A total of 988 subjects were avalaible for statistic analysis of dyslipemia; 320 patients had diabetes mellitus (DM); 178 had at least one cardiovascular disease without diabetes and 506 patients without those diseases were used as control.

Results: Total cholesterol and low density lipoprotein (LDL) fraction were higher in the group control. High density lipoprotein (HDL)-cholesterol was lower in the group DM as compared to control. Triglycerides were higher in group DM. Women had higher HDL-cholesterol and lower triglycerides levels than men. Only 26.6% of diabetics subjetcs and 28.9% of group ECV were well controlled; 42.5% of the control group had LDL cholesterol < 130 mg/dl. 13.3% of diabetics patients suffering from coronary artery disease had LDL-cholesterol < 70 mg/dl. They were taking statins: DM, 56.6); ECV 61.6%; and control, 39.4%. From patients who did not take cholesterol lowering drugs 51.6% in group DM and 33.8% in group ECV would need to take them.

Conclusions: The study shows a poor control of dyslipemia in diabetics subjects and high risk patients in spite of lower lipid levels when compared to lower risk population and a more frequent use of cholesterol lowering drugs. Nevertheless, statin use is still lower than currently recommended.

Publication types

  • Comparative Study
  • English Abstract
  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anticholesteremic Agents / therapeutic use
  • Comorbidity
  • Coronary Disease / blood
  • Coronary Disease / epidemiology
  • Cross-Sectional Studies
  • Diabetes Complications / blood*
  • Diabetes Complications / epidemiology
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Hypercholesterolemia / blood*
  • Hypercholesterolemia / drug therapy
  • Hypercholesterolemia / epidemiology
  • Hypertriglyceridemia / blood*
  • Hypertriglyceridemia / epidemiology
  • Lipids / blood*
  • Male
  • Middle Aged
  • Practice Guidelines as Topic
  • Prevalence
  • Risk Factors
  • Spain / epidemiology
  • Young Adult

Substances

  • Anticholesteremic Agents
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Lipids