Hodgkin lymphoma with cutaneous involvement

Dermatol Online J. 2009 May 15;15(5):5.

Abstract

We report a case of a 54-year-old previously healthy man with Hodgkin lymphoma who presented initially with a solitary cutaneous ulcer. Unlike non-Hodgkin lymphoma subtypes, skin involvement of Hodgkin lymphoma is extremely rare. Furthermore, the prognosis of Hodgkin lymphoma with skin infiltration is felt to be extremely poor. Contrary to other reports, this case demonstrates that a good response with standard therapy is possible.

Publication types

  • Case Reports

MeSH terms

  • Antigens, CD / analysis
  • Antigens, Neoplasm / analysis
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bleomycin / administration & dosage
  • Dacarbazine / administration & dosage
  • Doxorubicin / administration & dosage
  • Hodgkin Disease / diagnosis
  • Hodgkin Disease / drug therapy
  • Hodgkin Disease / pathology*
  • Humans
  • Lymph Nodes / chemistry
  • Lymph Nodes / pathology
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Reed-Sternberg Cells / pathology
  • Skin / chemistry
  • Skin / pathology*
  • Skin Ulcer / etiology
  • Vinblastine / administration & dosage

Substances

  • Antigens, CD
  • Antigens, Neoplasm
  • Bleomycin
  • Vinblastine
  • Dacarbazine
  • Doxorubicin

Supplementary concepts

  • ABVD protocol