[Testicular carcinoma and sarcoid-like necrotizing granulomatosis]

Ann Pathol. 2009 Jun;29(3):238-40. doi: 10.1016/j.annpat.2009.01.013. Epub 2009 Jun 10.
[Article in French]

Abstract

A 35-year-old man with a stage I non-seminomatous germ-cell tumor of the right testis was treated with a simple orchidectomy. Sixty-seven months later, the patient who was on clinical follow-up, has presented five bilateral lung nodules on computed-tomography scan. Additional staging showed no other abnormalities. Lung biopsy of two nodules was performed during a videothoracoscopy and the histologic examination revealed a sarcoidosis-like necrotizing granulomatosis. The coexistence of non-caseating granulomas and testis carcinoma showed an increase during the last two decades. The immunopathogenesis of sarcoid formation in malignant tumours is still unknown. During follow-up of patients with testicular carcinomas, the presence of lung nodules requires a histologic examination and sarcoidosis should be considered as differential diagnosis.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Humans
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / secondary
  • Male
  • Neoplasm Staging
  • Orchiectomy
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / etiology
  • Postoperative Complications / pathology
  • Sarcoidosis, Pulmonary / classification
  • Sarcoidosis, Pulmonary / diagnosis
  • Sarcoidosis, Pulmonary / etiology*
  • Sarcoidosis, Pulmonary / pathology
  • Testicular Neoplasms / complications*
  • Testicular Neoplasms / pathology
  • Testicular Neoplasms / surgery