Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results

Rev Soc Bras Med Trop. 2008:41 Suppl 2:95-8. doi: 10.1590/s0037-86822008000700019.

Abstract

In this study, the expression of chemokine receptors on the surface of circulating leukocytes was determined using flow cytometry. An increase in the percentage of CCR2+CD4+ lymphocytes was observed in the peripheral blood of leprosy patients. This preliminary data suggests that alterations occur in the chemokine receptor profile of these patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Case-Control Studies
  • Flow Cytometry
  • Humans
  • Leprosy / blood*
  • Leukocytes / chemistry*
  • Receptors, CCR2 / blood*
  • Receptors, CCR5 / blood*
  • Receptors, CXCR4 / blood*

Substances

  • Receptors, CCR2
  • Receptors, CCR5
  • Receptors, CXCR4