Alpha,alpha-dicyanoalkenes: versatile vinylogous nucleophiles for organic synthesis

Chem Commun (Camb). 2009 Aug 14:(30):4479-86. doi: 10.1039/b906201g. Epub 2009 May 27.

Abstract

Alpha,alpha-dicyanoalkenes are electron-deficient alkenes and inherently behave as electrophiles. Over the past five years some significant progress has been achieved by using alpha,alpha-dicyanoalkenes as vinylogous donors in C-C bond forming and other functionalisation reactions, especially for the construction of multifunctional products. In this feature article we will present the successful development of vinylogous reactions of alpha,alpha-dicyanoalkenes by our group and other groups.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry*
  • Catalysis
  • Cyclization
  • Electrons
  • Molecular Structure
  • Nitriles / chemistry*
  • Organic Chemistry Phenomena
  • Stereoisomerism
  • Vinyl Compounds / chemistry*

Substances

  • Alkenes
  • Nitriles
  • Vinyl Compounds