The Concern for management of intraocular inflammation has led to a continuing search for newer and more effective drugs. Though entry of antimetabolites, cytotoxic agents for the treatment of intraocular inflammation came as a great boon, latest research has been going on to improve the treatment modalities. Drugs like biologicals shows effective anti inflammatory action in uveitis patients. The aim of the present work was to compile a bibliographic review of the diverse potentially anti-inflammatory drugs along with some recent patents in an effort to systematize the current knowledge on this topic. Also the present work intends to show the mechanism of action of different anti-inflammatory drugs which will be a good benefit in the treatment of uveitis.