Paediatric germ cell tumours and congenital abnormalities: a Children's Oncology Group study

Br J Cancer. 2009 Aug 4;101(3):518-21. doi: 10.1038/sj.bjc.6605169. Epub 2009 Jul 14.

Abstract

Methods: Maternally reported congenital abnormalities (CAs) were examined in a case-control study of 278 cases of paediatric germ cell tumours (GCTs) and 423 controls.

Results and conclusions: Germ cell tumours were significantly associated with cryptorchidism in males (OR=10.8, 95% CI: 2.1-55.1), but not with any other specific CA in either sex.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Congenital Abnormalities*
  • Cryptorchidism / complications
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Neoplasms, Germ Cell and Embryonal / etiology*