Abstract
Some natural triterpenes exert a definite antiviral activity on several human viruses. New synthetic derivatives of glycyrrhizic acid (GL) are even more active than the parental molecule. GL can alter the expression of viral genes involved in cell transformation, thus opening a new window for speculating on viral cancerogenesis.
MeSH terms
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Animals
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Antiviral Agents / chemical synthesis
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Antiviral Agents / chemistry*
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Antiviral Agents / pharmacology*
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Gene Expression Regulation, Viral / drug effects
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Glycyrrhizic Acid / analogs & derivatives
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Glycyrrhizic Acid / chemical synthesis
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Glycyrrhizic Acid / chemistry*
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Glycyrrhizic Acid / pharmacology*
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Humans
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Viruses / drug effects*
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Viruses / genetics
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Viruses / growth & development
Substances
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Antiviral Agents
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Glycyrrhizic Acid