Abstract
The genetic control, mechanism of action and inhibition of aromatase for potential therapeutic benefits in the arena of hormone dependent illness continues to be of considerable interest. The work presented here concentrates on recent advances in the mechanistic aspects of the aromatase enzyme and the nature of the chemical entities that lead to its inhibition.
MeSH terms
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Animals
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology*
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Antineoplastic Agents / therapeutic use
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Aromatase / genetics
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Aromatase / metabolism*
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Aromatase Inhibitors / chemistry
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Aromatase Inhibitors / pharmacology*
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Aromatase Inhibitors / therapeutic use
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Breast Neoplasms / drug therapy
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Breast Neoplasms / enzymology*
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Humans
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Molecular Structure
Substances
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Antineoplastic Agents
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Aromatase Inhibitors
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Aromatase