[Incidence of chronic kidney disease in general population, EPIRAN study]

Nephrol Ther. 2009 Jun:5 Suppl 4:S250-5. doi: 10.1016/S1769-7255(09)74554-7.
[Article in French]

Abstract

Aims: To assess incidence of chronic kidney disease in general population and to describe baseline characteristics of incident patients.

Methods: Between 1st/01/04 and 30/06/06 all incident cases of chronic kidney disease in the Nancy district were prospectively identified. New cases were identified from all medical laboratories in this area and determined by a persistently increased serum creatinine level (> or = 150micromol/l, or paediatric levels) for 3 months after the 1st/01/04, and by living in Nancy area.

Results: The annual incidence rate of detected chronic kidney disease was 1 per thousand inhabitants (1,3 per thousand for men and 0,7 per thousand for women). Incidents patients were old (mean age: 77 years) and with numerous comorbidities (diabetes: 34 %, cardiac failure: 23 %). More than 30% of incident patients were diagnosed at sever stage of chronic kidney disease (<30ml/min/1,73m(2)).

Conclusions: The annual incidence of diagnosed chronic kidney disease is common: 10 times more than end-stage renal disease in France. Most of these patients are diagnosed in a severe stage of chronic kidney disease whereas they could be detected earlier and benefit from adequate, appropriate and multidisciplinary take care.

Publication types

  • English Abstract
  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Child
  • Child, Preschool
  • Chronic Disease
  • Creatinine / blood
  • Female
  • France / epidemiology
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Kidney Diseases / blood
  • Kidney Diseases / complications
  • Kidney Diseases / diagnosis*
  • Kidney Diseases / epidemiology*
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / epidemiology
  • Male
  • Middle Aged
  • Prospective Studies
  • Risk Factors
  • Sex Factors

Substances

  • Biomarkers
  • Creatinine