Aggressive course of disease in dementia

Serge Gauthier; Bruno Vellas; Martin Farlow; David Burn

doi:10.1016/j.jalz.2006.03.002

Aggressive course of disease in dementia

Alzheimers Dement. 2006 Jul;2(3):210-7. doi: 10.1016/j.jalz.2006.03.002.

Authors

Serge Gauthier¹, Bruno Vellas, Martin Farlow, David Burn

Affiliation

¹ McGill Centre for Studies in Aging, Verdun, Quebec, Canada. serge.gauthier@mcgill.ca

PMID: 19595889
DOI: 10.1016/j.jalz.2006.03.002

Abstract

The rate of disease progression in Alzheimer's disease (AD) patients is variable. A significant proportion of AD patients appear to experience an aggressive course of disease, and this has a major impact on prognosis, the patients, and their caregivers and society in general. Here we review the current literature on an aggressive course of disease in dementia and how it can be recognized in clinical practice. We also discuss the options available for treating patients with this condition.