Comment on "Functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse"

Stefan Bittner; Heinz Wiendl; Sven G Meuth

doi:10.1016/j.imlet.2009.07.002

Comment on "Functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse"

Immunol Lett. 2009 Aug 15;125(2):156-7. doi: 10.1016/j.imlet.2009.07.002. Epub 2009 Jul 10.

Authors

Stefan Bittner, Heinz Wiendl, Sven G Meuth

PMID: 19595706
DOI: 10.1016/j.imlet.2009.07.002

Abstract

Modulation of the biophysical properties of potassium channel currents upon immunological synapse formation between T cells and antigen-presenting cells has been reported. Some comments on this work are discussed in the light of previously described TASK channels on T lymphocytes.

Publication types

Letter
Comment

MeSH terms

Animals
Antigen-Presenting Cells / immunology
Antigen-Presenting Cells / metabolism
Antigen-Presenting Cells / pathology
Cell Proliferation
Immunological Synapses / immunology
Immunological Synapses / metabolism*
Kv1.3 Potassium Channel / immunology
Kv1.3 Potassium Channel / metabolism*
Lymphocyte Activation
Mice
Nerve Tissue Proteins / immunology
Nerve Tissue Proteins / metabolism*
Potassium Channels, Tandem Pore Domain / immunology
Potassium Channels, Tandem Pore Domain / metabolism*
Protein Kinases / metabolism
T-Lymphocytes / immunology
T-Lymphocytes / metabolism*
T-Lymphocytes / pathology

Substances

Kv1.3 Potassium Channel
Nerve Tissue Proteins
Potassium Channels, Tandem Pore Domain
potassium channel subfamily K member 3
Protein Kinases