Impact of the American College of Cardiology/American Heart Association guidelines for interpretability of continuous electrocardiography on the association of silent ischemia with troponin release after major noncardiac surgery

J Electrocardiol. 2009 Sep-Oct;42(5):455-461.e1. doi: 10.1016/j.jelectrocard.2009.05.008.

Abstract

Introduction: Preexisting electrocardiographic abnormalities may limit accuracy of continuous electrocardiography (cECG) for ischemia determination. The American College of Cardiology/American Heart Association published criteria for the exclusion of unsuitable cECG curves from ST-segment interpretation. These criteria consider medication and 12-lead ECG findings (medication- and 12-lead ECG-based criteria) and cECG lead characteristics (cECG-based criteria).

Methods: We recorded cECG in 300 patients undergoing major noncardiac surgery. We determined postoperative troponin and 12-month outcome. We compared the associations of cECG-detected ischemia with troponin and 12-month outcome with and without adherence to the criteria.

Results: Adherence to the medication- and 12-lead ECG-based criteria enhanced the association between troponin and perioperative ischemia in CM5 (odds ratio, 3.74; 95% confidence interval, 1.88-7.44) and 7.03 (2.67-18.49), respectively; P = .049). Similarly, the association between ischemia in CM5 and 12-month outcome tended to increase (P = .081).

Conclusions: Applying the guideline criteria for the interpretation of cECG enhanced cECG diagnostic value in surgical patients.

MeSH terms

  • Biomarkers / blood
  • Electrocardiography / standards*
  • Humans
  • Myocardial Ischemia / blood*
  • Myocardial Ischemia / diagnosis*
  • Myocardial Ischemia / surgery
  • Practice Guidelines as Topic*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Troponin I / blood*
  • United States

Substances

  • Biomarkers
  • Troponin I