Abstract
A multicomponent reaction of 1,3-dicarbonyls with 1,2-diamines and aromatic aldehydes is described for the direct stereoselective synthesis of 1,4-diazepane derivatives. Various reaction conditions were tested, including an efficient, user-friendly solvent- and catalyst-free procedure.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Azepines*
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Carbon Compounds, Inorganic / chemistry*
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Catalysis
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Cyclization
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Models, Molecular
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Molecular Structure
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Solvents
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Stereoisomerism
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Water / chemistry*
Substances
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Azepines
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Carbon Compounds, Inorganic
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Solvents
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Water