Intracystic papillary carcinoma of the male breast: a case report and review of the literature

Ir J Med Sci. 2012 Sep;181(3):329-31. doi: 10.1007/s11845-009-0372-y. Epub 2009 Jul 9.

Abstract

Introduction: Carcinoma of the male breast is an infrequent and poorly understood disease (Sinha et al. in Ann R Coll Surg Engl 88(5):W3-W5, 2006). It differs from female breast cancer in both demographic and histopathological characteristics.

Materials and methods: Herein we describe a case of intracystic papillary carcinoma in situ in a male breast with a review of the literature.

Conclusion: Although rare, in situ carcinoma constitutes a larger proportion of male than female breast cancer in a non-screened population. It is characteristically of the papillary and micropapillary subtype. Intracystic papillary carcinoma is a noncomedo intraductal carcinoma constituting about 0.5% of female breast cancers and is associated with a slightly inferior prognosis than other noncomedo intraductal carcinomas (Lefkowitz et al. in Hum Pathol 25:802-809, 1994).

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Agents, Hormonal / therapeutic use
  • Breast Neoplasms, Male / drug therapy
  • Breast Neoplasms, Male / pathology*
  • Breast Neoplasms, Male / surgery*
  • Carcinoma, Ductal, Breast / drug therapy
  • Carcinoma, Ductal, Breast / pathology*
  • Carcinoma, Ductal, Breast / surgery*
  • Chemotherapy, Adjuvant
  • Humans
  • Male
  • Mastectomy
  • Middle Aged
  • Tamoxifen / therapeutic use

Substances

  • Antineoplastic Agents, Hormonal
  • Tamoxifen