k-t PCA: temporally constrained k-t BLAST reconstruction using principal component analysis

Magn Reson Med. 2009 Sep;62(3):706-16. doi: 10.1002/mrm.22052.

Abstract

The k-t broad-use linear acquisition speed-up technique (BLAST) has become widespread for reducing image acquisition time in dynamic MRI. In its basic form k-t BLAST speeds up the data acquisition by undersampling k-space over time (referred to as k-t space). The resulting aliasing is resolved in the Fourier reciprocal x-f space (x = spatial position, f = temporal frequency) using an adaptive filter derived from a low-resolution estimate of the signal covariance. However, this filtering process tends to increase the reconstruction error or lower the achievable acceleration factor. This is problematic in applications exhibiting a broad range of temporal frequencies such as free-breathing myocardial perfusion imaging. We show that temporal basis functions calculated by subjecting the training data to principal component analysis (PCA) can be used to constrain the reconstruction such that the temporal resolution is improved. The presented method is called k-t PCA.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Artificial Intelligence
  • Cardiac-Gated Imaging Techniques / methods*
  • Cluster Analysis
  • Computer Graphics
  • Computer Simulation
  • Heart / anatomy & histology*
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / instrumentation
  • Magnetic Resonance Imaging / methods*
  • Models, Biological
  • Models, Statistical
  • Numerical Analysis, Computer-Assisted
  • Pattern Recognition, Automated / methods*
  • Phantoms, Imaging
  • Principal Component Analysis
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted
  • Subtraction Technique*
  • User-Computer Interface