Effect of lactoferrin and iron on the growth of human pathogenic Candida species

Pak J Biol Sci. 2009 Jan 1;12(1):91-4. doi: 10.3923/pjbs.2009.91.94.

Abstract

Effect of lactoferrin and iron have been studied on the multiplication and pseudohyphae production by three pathogenic Candida species viz., C. albicans, C. krusei and C. tropicalis. Results showed that lactoferrin showed significant antifungal effect on the three species tested, while the addition of iron enhance the multiplication of Candida species.

MeSH terms

  • Animals
  • Candida / drug effects*
  • Candida / pathogenicity
  • Humans
  • Iron / metabolism*
  • Lactoferrin / pharmacology*
  • Microbial Sensitivity Tests
  • Milk / chemistry
  • Milk / microbiology

Substances

  • Iron
  • Lactoferrin