Antioxidative phenylpropanoid-substituted epicatechin glycosides from Parabarium huaitingii

Planta Med. 2009 Dec;75(15):1586-90. doi: 10.1055/s-0029-1185836.

Abstract

Three new phenylpropanoid-substituted epicatechin glycosides, namely parabarosides A - C ( 1- 3), together with three known compounds, 5-caffeoylquinic acid (4), 5-caffeoylshikimic acid (5), and 3,4-dicaffeoylquinic acid (6), were obtained from the plant Parabarium huaitingii. Their structures were determined and full assignments of (1)H- and (13)C-NMR spectroscopic data were achieved by analyses of 1D- and 2D-NMR, mass, and CD spectra. The oxygen radical absorbance capacity (ORAC) assay was applied to evaluate their antioxidative capacity in vitro, which revealed that 1- 6 showed strong antioxidative properties.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology
  • Apocynaceae / chemistry*
  • Catechin / analogs & derivatives*
  • Catechin / chemistry
  • Catechin / isolation & purification
  • Catechin / pharmacology
  • Molecular Structure
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology
  • Plant Stems
  • Propanols / isolation & purification
  • Propanols / pharmacology

Substances

  • Antioxidants
  • Plant Extracts
  • Propanols
  • parabaroside A
  • parabaroside B
  • parabaroside C
  • 1-phenylpropanol
  • Catechin