Affy exon tissues: exon levels in normal tissues in human, mouse and rat

Bioinformatics. 2009 Sep 15;25(18):2442-3. doi: 10.1093/bioinformatics/btp414. Epub 2009 Jul 1.

Abstract

Summary: Most genes in human, mouse and rat produce more than one transcript isoform. The Affymetrix Exon Array is a tool for studying the many processes that regulate RNA production, with separate probesets measuring RNA levels at known and putative exons. For insights on how exons levels vary between normal tissues, we constructed the Affy Exon Tissues track from tissue data published by Affymetrix. This track reports exon probeset intensities as log ratios relative to median values across the dataset and renders them as colored heat maps, to yield quick visual identification of exons with intensities that vary between normal tissues.

Availability: Affy Exon Tissues track is freely available under the UCSC Genome Browser (http://genome.ucsc.edu/) for human (hg18), mouse (mm8 and mm9), and rat (rn4).

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Computational Biology / methods*
  • Databases, Genetic
  • Exons*
  • Gene Expression Profiling
  • Genome-Wide Association Study
  • Humans
  • Mice
  • Oligonucleotide Array Sequence Analysis
  • RNA / metabolism
  • Rats
  • Software

Substances

  • RNA