[Preparation of compound PuHuang granules and its clinical efficacy]

Zhong Yao Cai. 2009 Mar;32(3):470-2.
[Article in Chinese]

Abstract

Objective: To prepare Compound PuHuang Granules and observe its clinical efficacy on cerebral infarction.

Methods: The Compound PuHuang Granules were prepared and the identification was performed by TLC. A total of 328 patients with cerebral infarction were randomly divided into two groups and observed. 197 cases in the trial group were administered with Compound PuHuang Granules for 2 weeks, and 131 cases in the control group were administered with NaoXueShuan Tablets for 2 weeks as well.

Results: The method of identification was proved to be specific and reproductive. The effective rates of the trial group and the control group on vertigo, hemiplegia, numbness of extremities were 88.71%, 82.46%, 84.38% and 61.11%, 62.07%, 66.67%, respectively, which showed significances between the two groups (P < 0.05). But the effective rates of two groups on language disorder showed no signifcance.

Conclusions: The Compound PuHuang Granules is feasible in preparation and it has obvious efficacy, therefore, it would be useful in the clinical applications.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Administration, Oral
  • Adult
  • Animals
  • Blood Pressure / drug effects
  • Cerebral Infarction / blood
  • Cerebral Infarction / drug therapy*
  • Cerebral Infarction / physiopathology
  • Drug Combinations
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology
  • Drugs, Chinese Herbal / therapeutic use*
  • Female
  • Fibrinolytic Agents / pharmacology
  • Fibrinolytic Agents / therapeutic use*
  • Humans
  • Leeches / chemistry
  • Lipids / blood
  • Male
  • Middle Aged
  • Phytotherapy
  • Plants, Medicinal / chemistry*
  • Quality Control
  • Technology, Pharmaceutical / methods*

Substances

  • Drug Combinations
  • Drugs, Chinese Herbal
  • Fibrinolytic Agents
  • Lipids