Pneumonitis caused by silicone gel following breast implant rupture

Ir J Med Sci. 2010 Mar;179(1):141-5. doi: 10.1007/s11845-009-0369-6. Epub 2009 Jun 30.

Abstract

Introduction: There have been reports of pneumonitis associated with subcutaneous injection of liquid silicone, and of other pulmonary conditions due to cohesive silicone gel prostheses, but we know of no previous cases of pneumonitis associated with silicone gel.

Materials and methods: We report the case of a patient with a cohesive silicone gel mammary prosthesis in whom silicone-induced pneumonitis was diagnosed following radiological observation of pulmonary infiltrates and tests including transbronchial biopsy, which revealed the presence of silicone in alveolar histiocytes and small blood vessels.

Conclusion: Following removal of the ruptured prosthesis and a course of systemic corticoids, the patient progressed favourably.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Breast Implants / adverse effects*
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Middle Aged
  • Pneumonia / chemically induced*
  • Pneumonia / drug therapy
  • Pneumonia / etiology
  • Pneumonia / surgery
  • Prednisone / therapeutic use
  • Radiography
  • Rupture / complications
  • Rupture / diagnostic imaging
  • Rupture / surgery
  • Silicone Gels / adverse effects*
  • Silicone Gels / toxicity

Substances

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Silicone Gels
  • Prednisone