Comparison of degree of stenosis and plaque volume for the assessment of carotid atherosclerosis using 2-D ultrasound

Ultrasound Med Biol. 2009 Sep;35(9):1436-42. doi: 10.1016/j.ultrasmedbio.2009.03.013. Epub 2009 Jun 26.

Abstract

The degree of carotid stenosis (%ST) remains the most frequently used parameter for identifying patients with high risk of stroke but the relationship between %ST and the occurrence of stroke remains controversial. The objectives of this study were to check (1) the relationship between the %ST and the plaque volume index (PVI) as measured by echography and Doppler, (2) the relationship between the intima media thickness (IMT), a vessel wall remodeling index and the PVI an atheromatous growth index. For each of the 128 patients, (165 carotid stenosis), we measured the % ST (section or diameter), the max stenosis velocity (V(max)), the PVI and the common carotid IMT. The %ST (section) ranged from 10% to 93% (mean 66+/-18), V(max) from 0.3m/s to 3m/s (mean 1.2+/-0.8), PVI from 0.61cm(3) to 1.17cm(3) (mean 0.41+/-0.21) and the IMT from 0.08cm up to 0.31cm (mean 0.12+/-0.03). There was no significant correlation between either PVI and %ST (section or diameter), PVI and minimal stenosis section area (S1) or between PVI and V(max). There was no significant correlation between IMT and both %ST area and PVI. PVI was significantly correlated with the whole artery section area (S2) and the plaque length (L). The %ST (section or diameter) was significantly correlated with S1 but not with S2. The absence of correlation between the PVI and the %ST confirm that these two parameters describe two different processes of the atheromatous development.

MeSH terms

  • Aged
  • Blood Flow Velocity
  • Carotid Artery, Common / diagnostic imaging
  • Carotid Artery, Common / pathology
  • Carotid Stenosis / complications
  • Carotid Stenosis / diagnostic imaging*
  • Carotid Stenosis / pathology
  • Echoencephalography / methods
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted / methods
  • Male
  • Middle Aged
  • Models, Cardiovascular
  • Risk Assessment / methods
  • Stroke / etiology
  • Tunica Intima / diagnostic imaging
  • Tunica Intima / pathology
  • Tunica Media / diagnostic imaging
  • Tunica Media / pathology