Palliative treatment of inoperable malignant tracheobronchial obstruction: temporary stenting combined with radiation therapy and/or chemotherapy

AJR Am J Roentgenol. 2009 Jul;193(1):W38-42. doi: 10.2214/AJR.08.2037.

Abstract

Objective: The purpose of our study was to evaluate the clinical results of temporary stenting followed by radiation and/or chemotherapy in patients with inoperable malignant tracheobronchial strictures.

Conclusion: Temporary stenting combined with radiation therapy and/or chemotherapy may be clinically effective in the palliative treatment of patients with malignant tracheobronchial strictures. Stent placement may serve as an effective bridge to radiation and/or chemotherapy, allowing the latter to consolidate durable relief of obstructing symptoms by reducing tumor burden. Furthermore, our treatment strategy may increase patients' quality of life by reducing stent-related complications.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Bronchial Diseases / etiology*
  • Bronchial Diseases / therapy*
  • Combined Modality Therapy
  • Female
  • Head and Neck Neoplasms / complications*
  • Humans
  • Male
  • Middle Aged
  • Palliative Care / methods
  • Radiotherapy, Conformal / methods*
  • Stents*
  • Tracheal Stenosis / etiology*
  • Tracheal Stenosis / therapy*
  • Treatment Outcome

Substances

  • Antineoplastic Agents