Changes in endolymphatic hydrops in a patient with Meniere's disease observed using magnetic resonance imaging

Auris Nasus Larynx. 2010 Apr;37(2):220-2. doi: 10.1016/j.anl.2009.04.013. Epub 2009 Jun 21.

Abstract

We describe a case report of a patient with Meniere's disease whose changes in endolymphatic hydrops were observed using magnetic resonance imaging (MRI). Gadolinium was injected intratympanically through the tympanic membrane, and MRI scans performed with a 3-T MRI unit revealed endolymphatic hydrops inside the perilymphatic space filled with gadolinium. We evaluated the relationship between the image findings and hearing level. The correlation between the degree of endolymphatic hydrops observed by MRI and hearing level in patients with Meniere's disease offers a promising new method to study the progression of Meniere's disease.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Audiometry, Evoked Response
  • Audiometry, Pure-Tone
  • Caloric Tests
  • Contrast Media / administration & dosage
  • Disease Progression
  • Endolymphatic Hydrops / diagnosis*
  • Endolymphatic Hydrops / physiopathology
  • Evoked Potentials, Motor / physiology
  • Gadolinium DTPA
  • Hearing Loss, Sensorineural / diagnosis
  • Hearing Loss, Sensorineural / physiopathology
  • Humans
  • Image Enhancement*
  • Image Processing, Computer-Assisted*
  • Imaging, Three-Dimensional*
  • Magnetic Resonance Imaging*
  • Male
  • Meniere Disease / diagnosis*
  • Meniere Disease / physiopathology
  • Sensitivity and Specificity
  • Syncope / etiology
  • Syncope / physiopathology

Substances

  • Contrast Media
  • gadodiamide
  • Gadolinium DTPA