Corticosteroids 21-glucuronides: synthesis and complete characterization by (1)H and (13)C NMR

Pierangela Ciuffreda; Silvana Casati; Maria De Mieri; Patrizia Ferraboschi

doi:10.1016/j.steroids.2009.06.003

Corticosteroids 21-glucuronides: synthesis and complete characterization by (1)H and (13)C NMR

Steroids. 2009 Oct;74(10-11):870-5. doi: 10.1016/j.steroids.2009.06.003. Epub 2009 Jun 16.

Authors

Pierangela Ciuffreda¹, Silvana Casati, Maria De Mieri, Patrizia Ferraboschi

Affiliation

¹ Dipartimento di Scienze Precliniche LITA Vialba, Università degli Studi di Milano, 20157 Milano, Italy.

PMID: 19538978
DOI: 10.1016/j.steroids.2009.06.003

Abstract

Despite the important physiological role of the corticosteroids glucuronides, very poor NMR data for this class of compounds are reported. For this reason we prepared a set of corticosteroids and submitted them to a detailed NMR study. A complete assignment of (1)H and (13)C signals was accomplished arranging mono- and two-dimensional NMR techniques.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adrenal Cortex Hormones / chemical synthesis*
Adrenal Cortex Hormones / chemistry*
Glucuronides / chemical synthesis*
Glucuronides / chemistry*
Magnetic Resonance Spectroscopy
Mass Spectrometry

Substances

Adrenal Cortex Hormones
Glucuronides