Practices for prevention, diagnosis and management of postpartum haemorrhage: impact of a regional multifaceted intervention

BJOG. 2009 Sep;116(10):1325-33. doi: 10.1111/j.1471-0528.2009.02238.x. Epub 2009 Jun 17.

Abstract

Objective: To evaluate the effectiveness of a multifaceted intervention on practices for prevention, diagnosis and management of postpartum haemorrhage (PPH) and on the prevalence of major PPH in a French perinatal network.

Design: Quasi-experimental before-and-after survey.

Setting: All maternity units (n = 19) of a French administrative region, operating as a perinatal network.

Sample: One representative sample of all women delivering in the network, one representative sample of women with PPH deliveries and an exhaustive sample of women with major PPH.

Methods: The multifaceted intervention took place between February 2003 and March 2004. Information was retrospectively collected for two periods, 2002 (before the intervention) and 2005 (after).

Main outcome measures: Practices for prevention, diagnosis and management of PPH and prevalence of major PPH.

Results: After the intervention, the pharmacological prevention of PPH increased from 58.8% to 75.9% of vaginal deliveries (P < 10(-4)), and the use of blood collecting bags from 3.9% to 76.3% (P < 10(-4)), but initial PPH management did not change significantly. However, the median delay for second-line pharmacological treatment was significantly shortened [from 80 min (35-130) in 2002 to 32.5 min (20-75) in 2005]. An increase was observed in the use of surgery for PPH (0.06% versus 0.12% of deliveries; P = 0.03) and in blood transfusions (0.18% versus 0.33%; P = 0.01). The prevalence of major PPH did not change (0.80% versus 0.86% of deliveries; P = 0.62).

Conclusions: The intervention was effective at improving PPH-related preventive and diagnostic practices in a perinatal network. Improving management practices and reducing the prevalence of major PPH might require a different intervention design.

Publication types

  • Evaluation Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortifacient Agents, Nonsteroidal / administration & dosage
  • Adult
  • Clinical Protocols / standards*
  • Dinoprostone / administration & dosage
  • Dinoprostone / analogs & derivatives
  • Female
  • Hospitals, Maternity / standards*
  • Humans
  • Infusions, Intravenous
  • Oxytocics / administration & dosage
  • Oxytocin / administration & dosage
  • Postpartum Hemorrhage* / diagnosis
  • Postpartum Hemorrhage* / prevention & control
  • Postpartum Hemorrhage* / surgery
  • Practice Guidelines as Topic
  • Pregnancy
  • Professional Practice / standards*
  • Prospective Studies
  • Specimen Handling
  • Treatment Outcome

Substances

  • Abortifacient Agents, Nonsteroidal
  • Oxytocics
  • Oxytocin
  • sulprostone
  • Dinoprostone