Synthesis and characterization of a photoluminescent nanoparticle based on fullerene-silica hybridization

Angew Chem Int Ed Engl. 2009;48(29):5296-9. doi: 10.1002/anie.200901750.

Abstract

Bright lights: Fullerene-silica hybrid nanoparticles have bright photoluminescence, high photostability, and low cytotoxicity, which are assets for bioimaging agents. The origin of the photoluminescence of the nanoparticle is the C-O-Si bond (see picture).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Cell Membrane Permeability
  • Cell Survival / drug effects
  • Fullerenes / chemistry*
  • Fullerenes / pharmacokinetics
  • Fullerenes / toxicity*
  • Luminescence
  • Luminescent Agents / chemistry*
  • Luminescent Agents / pharmacokinetics
  • Luminescent Agents / toxicity
  • Macrophages / cytology
  • Macrophages / drug effects
  • Mice
  • Nanoparticles / chemistry*
  • Nanoparticles / toxicity*
  • Nanoparticles / ultrastructure
  • Silicon Dioxide / chemistry*
  • Silicon Dioxide / pharmacokinetics
  • Silicon Dioxide / toxicity*

Substances

  • Fullerenes
  • Luminescent Agents
  • Silicon Dioxide