Effects of two different type of treadmill running on human blood leukocyte populations and inflammatory indices in young untrained men

J Sports Med Phys Fitness. 2009 Jun;49(2):214-23.

Abstract

Aim: The aim of this study was to investigate inflammatory markers and muscle damage indices in response to two different intensity exercises, eighteen young volunteers participated in this study.

Methods: The participants were randomly divided into two groups: moderate exercise (60% VO(2) max) and intensive exercise (75% VO(2) max). Each group had to run on the treadmill for 30 minutes. Blood samples were collected before, immediately after and two hours after exercise to determine IL-6, CK, CRP and WBC.

Results: Blood inflammatory markers and muscle damage indices levels significantly increased in both exercise groups immediately after exercise (P<0.05), but there was no significant difference between the two groups (a time * group effects) in all of the variables (P>0.05).

Conclusions: The results of the present study suggest that in young untrained males, exercise intensity cannot be considered as the main factor that determines the inflammatory responses and aerobic exercise, regardless of intensity, results in increased plasma inflammatory responses.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Biomarkers / blood*
  • C-Reactive Protein / metabolism
  • Creatine Kinase / blood
  • Exercise / physiology
  • Exercise Tolerance / physiology
  • Humans
  • Inflammation / blood
  • Interleukin-6 / blood
  • Leukocytes / metabolism*
  • Male
  • Running / physiology*
  • Young Adult

Substances

  • Biomarkers
  • Interleukin-6
  • C-Reactive Protein
  • Creatine Kinase